SajStorLab

Granulocyte-macrophage colony-stimulating factor is a hematopoietic growth factor and an immune response modulator. Human GM-CSF is a 127 amino acid monomeric protein with two glycosylation sites. The variability in glycosylation results in differences in molecular weight ranging from 14 kDa to 35 kDa. Non-glycosylated and glycosylated GM-CSF show similar activity in vitro.

The family of interferons (IFNs) are glycoprotein proteins that have a wide range of biological activity, including antiviral, antitumor, and also exhibit antiproliferative and proapoptotic properties. There are three known types of interferons: type I IFN / type I IFN (α, β, ω, τ, κ, ˜, and δ), type II IFN / type II IFN (γ), and type III IFN / type III IFN (λ1 (IL-29), λ2 (IL-28A), λ3 (IL-28B)). The classification of interferons by type is based on their interaction with the corresponding cellular receptors. Type I and II IFN receptors are present on the surface of most human cells, while type III IFN receptors are highly expressed on hepatocytes, but absent on the surface of microvascular endothelial cells, adipocytes, fibroblasts, and cells of the central nervous system.

Insulin-like human growth factor I is a protein from the family of insulin-like growth factors, a hormone with a pleiotropic effect, which is involved in the growth processes of cell proliferation and differentiation, promotes cell survival, maintains their functions, and has anabolic effects.