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The dNTP mixture is an aqueous solution of four highly purified 2’-deoxynucleoside-5’-triphosphates (dATP, dTTP, dHTF, dCTF) in equimolar concentration

Genta-ExoI exonuclease I hydrolyzes single-stranded DNA in the 3'→ 5' direction, releasing deoxyribonucleoside 5'-monophosphate. It does not cleave DNA chains whose 3’-end is blocked by a phosphoryl or acetyl group. Active in the PCR buffer. Isolated from a strain of Escherichia coli expressing the exonuclease I gene of E.coli.

The ALSENSE Forensic reagent kit is designed to determine and evaluate the amount of human genomic DNA and gender by real-time polymerase chain reaction in human biological material. The reagent kit is intended for use in criminology, as well as PCR research in biology and medicine. The reagent kit is based on the polymerase chain reaction method with hybridization-fluorescence detection in real time (PCR-RV) using specific TaqMan probes. Amplification of multi-copy autosomal fragments of different sizes allows for a reliable assessment of the amount of DNA in the sample under study, and amplification of a multi-copy fragment of the Y chromosome to determine gender.

Medicines may contain pyrogens, the sources of which can be bacteria, viruses, fungi, and pyrogens can also be by-products of the production process. Contamination of drugs with pyrogenic substances is a serious threat to the health of patients and can lead to the development of fever and, ultimately, shock and death. Currently, to determine the content of pyrogenic substances (bacterial endotoxins and substances of non-endotoxin nature), the “Pyrogenicity” test is used, carried out on rabbits, which is inaccurate and harmful to animals. The monocyte activation test (MAT) has higher sensitivity and does not require the use of animals.

The kit is based on multiplex amplification of 28 STR loci followed by separation of PCR products by capillary electrophoresis. Of these, 25 autosomal loci: D3S1358, D2S441, D1S1656, D19S433, TPOX, D2S1338, TH01, D16S539, CSF1PO, D18S51, D21S11, D22S1045, D8S1179, VWA, D5S818, FGA, D13S31 7, D7S820, D12S391, D10S1248, SE33, DYS391, D8S1132, D7S1517, Penta D, Penta E and 3 sex loci: Amelogenin, Yindel, DYS391. The STR loci presented in the set are highly polymorphic, which allows for reliable identification of a person. The set includes all loci from the CODIS (Combined DNA Index System) and ESS (European Standard Set) databases, as well as loci SE33, Penta D, Penta E. To obtain the complete (for all 28 STR loci) genotype of the test sample, 0.125 nanograms (ng) of non-degraded DNA is sufficient. The optimal amount of DNA introduced into the reaction is 1 ng. The range of DNA concentrations for amplification is from 0.1 to 4 ng per reaction.

Release form 1:

• – a set of reagents for manual RNA isolation and at automated stations using the M-Sorb-NK magnetic separation method;
• – a set of reagents for RT-PCR-RT analysis “CoV-2-FluA/B-RT-PCR”

Note: format 1 - lyophilized in flexible strips, for Rotor-Gene devices and plate cyclers or format 2 - lyophilized in PCR plates
Release form 2:

• - a set of reagents for RT-PCR-RT analysis “CoV-2-FluA/B-RT-PCR”
• Note: format 1 - lyophilized in flexible strips, for Rotor-Gene devices and plate cyclers or format 2 - lyophilized in PCR plates