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Insulin-like human growth factor I is a protein from the family of insulin-like growth factors, a hormone with a pleiotropic effect, which is involved in the growth processes of cell proliferation and differentiation, promotes cell survival, maintains their functions, and has anabolic effects.

Interleukin 4 is a pleiotropic cytokine that regulates the cellular and humoral immune response and is involved in the processes of proliferation, differentiation, and activation of cells of various types. IL-4 is expressed by activated T lymphocytes, mast cells, dendritic cells, NKT cells, basophils, eosinophils. The epithelium and tumor cells are sources of IL-4 in tissues.

Human Serum Albumin (HSA) is the main human plasma protein and has many physiological properties due to its unique structure.

Vascular Endothelial Growth Factor is one of the key regulators of angiogenesis. The most important role in the human body is played by a protein of the VEGF family called VEGF-A. VEGF-A is a 45 kDa glycoprotein homodimer and plays a key role in chemotaxis and angioblast differentiation, endotheliocyte (EC) proliferation, vasculogenesis, and vascular remodeling. As a result of alternative splicing or proteolytic cleavage, 4 main isoforms of VEGF-A are formed, consisting of 121, 165, 189, or 206 amino acid residues.

Thrombopoietin is a glycoprotein hormone synthesized mainly in the liver, the main physiological regulator of platelet production. Participates in the development of precursors of other blood cells. TPO and other TPO receptor agonists are promising therapeutic agents.

Interleukin 3 is a cytokine, a multipotent colony-stimulating hematopoietic factor, produced mainly by activated T-lymphocytes. The main function of IL-3 is participation in the differentiation and proliferation of myeloid precursor cells. IL-3 is involved in the pathogenesis of a number of diseases, including hematological tumors. IL-3 is a therapeutic agent in the treatment of conditions associated with insufficient hematopoietic function of the bone marrow.

Erythropoietin (EPO) is a cytokine (glycoprotein) that stimulates erythropoiesis.

Stem cell factor is a growth factor produced mainly by fibroblasts and endothelial cells. The cytokine SCF plays an important role in the survival and proliferation of hematopoietic cells, melanocytes and germ cells, their migration and differentiation.

Leukemiainhibitoryfactor (LIF), also known as differentiation stimulating factor (D factor) or melanoma-derived LPL inhibitor (MLPLI). LIF is involved in the regulation of hematopoiesis, bone metabolism, neurodevelopment, and inflammation.

Fibroblast growth factor-2 is a member of the fibroblast growth factor family. It has mitogenic activity against target cells, is a neurotrophic factor, participates in the regulation of angiogenesis, individual development, tissue regeneration, reproduction and pathogenesis of a number of diseases, including malignant tumors.

Nojin is a protein involved in the development of various tissues, including bone, muscle and nerve. It is an antagonist of bone morphogenetic proteins (MBPs). Noggin has been implicated in a number of pathological conditions.

IL-15 is a pleiotropic cytokine. It is essential for the development, survival, and activation of NK cells. Participates in the induction of cytotoxic effector cells. Acting as an interleukin-2 antagonist, IL-15 contributes to the maintenance of CD8+ T memory cells and the maintenance and survival of CD4+ and CD8+ T lymphocytes. Acts on a number of other cells.